Tigers vs Guardians Odds and Free Prediction [9/23/25]

Detroit (85-71) at Cleveland (84-72)
When: Tuesday, September 23rd 2025
Where: Progressive Field,
Cleveland, OH

Time: 6:40 ET | TV: mlb.tv
Opening Odds: Detroit -158/7

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Tigers vs Guardians Recent Meetings

DateHome/AwayH StarterA StarterLineO/U
9/18/25DET 1 - CLE 3T. SkubalT. Bibee-225/7U
9/17/25DET 0 - CLE 4J. FlahertyG. Williams-150/8U
9/16/25DET 5 - CLE 7 xC. MizeJ. Cantillo-145/8O
7/6/25CLE 2 - DET 7 xG. WilliamsT. Skubal185/7O
7/5/25CLE 0 - DET 1L. AllenC. Mize120/9U
7/4/25CLE 1 - DET 2S. CecconiR. Olson105/8.5U
5/25/25DET 5 - CLE 0T. SkubalL. Allen-298/6.5U
5/24/25DET 5 - CLE 7 xC. MizeL. Ortiz-140/8O
5/23/25DET 1 - CLE 3J. JobeS. Cecconi-104/8.5U
5/22/25DET 0 - CLE 7J. FlahertyT. Bibee-119/8U
2024 Season
10/12/24CLE 7 - DET 3M. BoydT. Skubal100/6O
10/10/24DET 4 - CLE 5R. OlsonT. Bibee111/6.5O
10/9/24DET 3 - CLE 0K. MonteroA. Cobb103/7.5U
10/7/24CLE 0 - DET 3M. BoydT. Skubal114/6U
10/5/24CLE 7 - DET 0T. BibeeT. Holton-128/7P
7/30/24DET 0 - CLE 5T. HoltonG. Williams117/8U
7/29/24DET 4 - CLE 8B. BrieskeT. Bibee142/7.5O
7/25/24CLE 0 - DET 3G. WilliamsT. Holton-142/7.5U
7/24/24CLE 2 - DET 1T. BibeeJ. Flaherty-137/7U
7/23/24CLE 5 - DET 4X. CurryT. Holton-127/8.5O
Courtesy of Don Best Sports

Tarik Skubal L10 Starts

DatevsS/RResScoreIPHRERKBBHRPP/IPGB:FB
9/18/25CLESND1-36.071192110217.02.00
9/12/25@ MIASL2-83.14442024513.53.00
9/6/25CHWSW6-07.02006109012.92.67
8/31/25@ KCSW5-07.04004209313.31.00
8/25/25@ ATHSL3-86.276112029914.81.00
8/19/25HOUSND1-07.030010209513.61.67
8/14/25@ MINSND4-37.06333219914.12.25
8/8/25LAASND6-54.26446229219.71.00
8/2/25@ PHISW7-57.053310019814.01.00
7/26/25TORSND1-66.05007309616.01.67
Courtesy of Don Best Sports

Gavin Williams L10 Starts

DatevsS/RResScoreIPHRERKBBHRPP/IPGB:FB
9/17/25@ DETSW4-05.030092010020.01.50
9/11/25KCSND3-26.042263110517.51.20
9/5/25@ TBSW7-17.07113319513.63.00
8/30/25SEASW4-37.04118119513.61.67
8/24/25@ TEXSL0-53.13333419027.0.00
8/18/25@ AZSW3-15.14005109918.61.00
8/13/25MIASND4-133.05444127525.01.50
8/6/25@ NYMSW4-18.211164112614.53.25
8/1/25MINSND3-26.04008209616.07.00
7/26/25@ KCSND3-56.05223217913.22.25
Courtesy of Don Best Sports


Prediction

At one point, we thought the American League Central was going to be the first division clinched this summer. The Tigers were dominating everyone and running away with it. Well, that’s why you play 162 games. In one of the most dramatic turnarounds I’ve ever seen, the Guardians are right back on Detroit’s heels. On September 10th, the Tigers had a 99% chance of winning the division. Since that date, Detroit is 1-10 and Cleveland is 10-1 and the lead is just one game.

We know Skubal is good, but Williams has actually been better lately. In his last five starts, Skubal has been hit hard twice, while Williams has had five straight starts of allowing three runs or less. Also, vs. Detroit this season, Williams has allowed four hits and zero runs over 11 innings. The fact that the Tigers are favored by this much on the road amazes me. Give me the red-hot Guardians at home.

Pick: Guardians +145

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