Chargers vs Raiders Odds and Free Prediction [9/15/25]

LA Chargers (1-0) at Las Vegas (1-0)
When: Monday, September 15th 2025
Where: Allegiant Stadium,
Las Vegas, NV

Time: 10:00 ET | TV: ESPN
Opening Odds: Los Angeles -3/44.5

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Chargers vs Raiders Recent Meetings

DateAway/HomeLineATSTotRusPasTotRusPas
1/5/25LAC (34) - LV (20)7/41.5LAC/O47313733626439225
9/8/24LV (10) - LAC (22)-3/41LAC/U31617614029671225
12/14/23LAC (21) - LV (63)-3/36.5LV/O32692234378124254
10/1/23LV (17) - LAC (24)-7/49P/U30515515026476188
12/4/22LAC (20) - LV (27)-2.5/49.5LV/U38672314404154250
9/11/22LV (19) - LAC (24)-3.5/53LAC/U3557627932064256
1/9/22LAC (32) - LV (35)3/49.5LV/O44085355346174172
10/4/21LV (14) - LAC (28)-3/52LAC/U38016821221348165
12/17/20LAC (30) - LV (27)-3.5/52.5LAC/O40296306449173276
11/8/20LV (31) - LAC (26)1/52.5LV/O440128312320160160
Courtesy of Don Best Sports

Chargers Injury Report

Player Status/Updated
Trey LanceQBQues Sept 15 - Hand - 9/6/25
Mekhi BectonGQues Sept. 15 - Illness - 9/6/25
Otito OgbonniaDLQues Sept. 15 - Undisclosed - 9/6/25
Elijah MoldenDBOut Mon - Hamstring - 9/13/25
Denzel PerrymanLBOut Mon - Ankle - 9/13/25
Josh HarrisLSOut indefinitely - Undisclosed - 8/28/25
Josh FugaDLout for season - Undisclosed - 8/27/25
Jordan OladokunCBout for season - Undisclosed - 8/27/25
Junior ColsonLBOut Indefinitely - Shoulder - 8/27/25
Deane LeonardDBOut indefinitely - Leg - 8/28/25
Eric RogersCBOut indefinitely - Undisclosed - 8/28/25
Rashawn SlaterOTout for season - Knee - 8/10/25
Savion WashingtonOTOut indefinitely - Undisclosed - 9/6/25
Courtesy of Don Best Sports

Raiders Injury Report

Player Status/Updated
Elandon RobertsLBQues Sept. 15 - Elbow - 9/7/25
Alex CappaGQues Sept. 15 - Ribs - 9/7/25
Leki FotuDTQues Sept. 15 - Foot - 9/7/25
Brock BowersTEQues Sept. 15 - Knee - 9/7/25
Jackson Powers-JohnsonCOut Mon - Ribs - 9/13/25
Aidan O'ConnellQBOut Indefinitely - Wrist - 8/28/25
Lonnie Johnson Jr.SEarly Oct - Lower Body - 8/29/25
Courtesy of Don Best Sports


Prediction

I’ll take the points in this one. The Chargers swept the Raiders last season, but Las Vegas has improved. They beat up the Patriots in Week 1 and Geno Smith had a big game under Chip Kelly’s up-tempo offense. Smith looked very comfortable and I expect another solid game. The Chargers are a little banged up on defense, but they will also put up some points against a suspect Raiders D. The home team is 6-1-1 ATS in the last eight meetings, so give me Las Vegas.

Pick: Raiders +3.5

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