San Francisco (13-5) at Seattle (14-3)
When: Saturday, January 17th 2026
Where: Lumen Field,
Seattle, WA
Time: 8:00 ET | TV: FOX
Opening Odds: Seattle -7/45.5
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49ers vs Seahawks Recent Meetings
Prediction
I’m going to ride this 49ers team once again this week despite all the injuries they have suffered this season. Seattle beat the Niners in the season finale to grab the No. 1 seed and force San Fran to go on the road and they took care of business at Philadelphia. The 49ers are now 8-2 on the road this season after their wild card win over the Eagles. San Fran has also dominated the series of late, winning seven of the last nine meetings. The Seahawks are just 4-4 ATS at home this season and 1-4 ATS in their last five when hosting the 49ers. I just don’t trust Sam Darnold when the game is on the line. Seattle may still win this game, but it won’t be a blowout.
Pick: 49ers +7
