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**All plays are Listed Pitchers and trends are courtesy of Don Best Sports and are through 7/21/25**
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Cincinnati (Lodolo) at Washington (Soroka) – 12:05 ET
Under is 9-3-1 in CIN last 13 overall.
Under is 9-3-1 in CIN last 13 on grass.
CIN are 5-14 in their last 19 Wed. games.
Over is 9-1 in WAS last 10 home games.
Over is 19-5-2 in WAS last 26 overall.
Over is 19-5-2 in WAS last 26 on grass.
Over is 7-3 in the last 10 meetings.
Pick: Nationals +122
San Diego (Cease) at Miami (Alcantara) – 12:10 ET
SD are 2-7 in their last 9 Wed. games.
SD are 6-2 in their last 8 games on grass.
SD are 6-2 in their last 8 overall.
Under is 20-7-1 in MIA last 28 home games.
MIA are 8-20 in their last 28 Wed. games.
Under is 11-5-1 in MIA last 17 on grass.
SD are 8-3 in the last 11 meetings.
Pick: Marlins +130
San Francisco (Verlander) at Atlanta (Strider) – 12:15 ET
Over is 20-5-1 in SF last 26 Wed. games.
Over is 7-2-1 in SF last 10 road games.
Under is 6-2 in Verlander’s last 8 starts overall.
ATL are 2-6 in their last 8 home games.
Under is 64-29-4 in ATL last 97 home games.
ATL are 23-7 in Strider’s last 30 home starts.
Under is 7-3-1 in the last 11 meetings.
Pick: Braves -1.5 +125
St Louis (Pallante) at Colorado (Gordon) – 3:10 ET
STL are 2-8 in their last 10 road games.
Over is 9-3-1 in STL last 13 on grass.
Over is 9-3-1 in STL last 13 overall.
COL are 12-41 in their last 53 home games.
COL are 13-44 in their last 57 Wed. games.
COL are 24-79 in their last 103 games on grass.
Pick: Rockies +1.5 +112
Baltimore (Eflin) at Cleveland (Cecconi) – 6:40 ET
BAL are 6-16 in their last 22 Wed. games.
Under is 17-7-1 in BAL last 25 road games.
CLE are 7-1 in their last 8 Wed. games.
CLE are 3-8 in their last 11 home games.
Under is 6-2 in Cecconi’s last 8 on grass.
Over is 7-0-1 in the last 8 meetings.
BAL are 8-18 in the last 26 meetings in Cleveland.
Pick: Orioles +115
NY Yankees (Fried) at Toronto (Bassitt) – 7:07 ET
Over is 9-2 in NYY last 11 road games.
Over is 13-3-1 in NYY last 17 on astroturf.
Under is 11-3-1 in NYY last 15 Wed. games.
TOR are 7-2 in their last 9 Wed. games.
TOR are 36-15 in their last 51 games on astroturf.
TOR are 36-15 in their last 51 home games.
Over is 10-1 in the last 11 meetings in Toronto.
Pick: Blue Jays +124
Chicago White Sox (Cannon) at Tampa Bay (Bradley) – 7:35 ET
CHW are 33-99 in their last 132 road games.
CHW are 60-153 in their last 213 games on grass.
CHW are 63-156 in their last 219 overall.
TB are 2-6 in their last 8 overall.
TB are 2-6 in their last 8 games on grass.
Under is 5-2-1 in TB last 8 overall.
CHW are 6-2 in the last 8 meetings.
Pick: White Sox +1.5 -118
Athletics (Sears) at Texas (Corbin) – 8:05 ET
Over is 6-2-2 in ATH last 10 Wed. games.
ATH are 8-22 in their last 30 road games.
ATH are 21-43 in their last 64 Wed. games.
Over is 8-1 in TEX last 9 vs. American League West.
TEX are 3-9 in their last 12 Wed. games.
Pick: A’s +130
Detroit (Melton) at Pittsburgh (Falter) – 12:35 ET
Over is 9-1 in DET last 10 interleague games.
DET are 1-7 in their last 8 overall.
DET are 1-7 in their last 8 games on grass.
PIT are 2-11 in their last 13 overall.
PIT are 2-11 in their last 13 games on grass.
PIT are 12-3 in their last 15 Wed. games.
Pick: Pirates +136
LA Angels (Burke) at NY Mets (Manaea) – 1:10 ET
Over is 10-1 in LAA last 11 overall.
Over is 17-5 in LAA last 22 on grass.
Over is 11-3-1 in NYM last 15 interleague games.
Over is 22-8 in NYM last 30 interleague home games.
NYM are 50-20 in their last 70 home games.
Under is 6-1-1 in the last 8 meetings.
Pick: Mets -1.5 +110
Kansas City (Lugo) at Chicago Cubs (Rea) – 2:20 ET
Under is 36-15-2 in KC last 53 Wed. games.
KC are 2-8 in Lugo’s last 10 interleague starts.
Under is 13-4 in Lugo’s last 17 road starts.
Under is 8-1-1 in CHC last 10 Wed. games.
Under is 8-2-1 in CHC last 11 interleague games.
CHC are 20-8 in their last 28 home games.
Pick: Royals +131
Houston (Walter) at Arizona (Pfaadt) – 3:40 ET
HOU are 16-5 in their last 21 interleague games.
HOU are 8-3 in their last 11 road games.
HOU are 3-7 in their last 10 games on grass.
AZ are 21-7 in their last 28 Wed. games.
Over is 11-4-1 in AZ last 16 home games.
Over is 20-8-1 in AZ last 29 Wed. games.
Pick: Diamondbacks -121
Milwaukee (Priester) at Seattle (Castillo) – 3:40 ET
Over is 9-2 in MIL last 11 Wed. games.
MIL are 19-7 in their last 26 road games.
MIL are 39-15 in their last 54 overall.
Over is 8-1-1 in SEA last 10 overall.
Over is 8-1-1 in SEA last 10 on grass.
Under is 6-2-1 in SEA last 9 home games.
MIL are 7-1 in the last 8 meetings.
Pick: Brewers +118
Minnesota (Paddack) at LA Dodgers (Glasnow) – 4:10 ET
Under is 7-1 in MIN last 8 road games.
Under is 12-3-1 in MIN last 16 Wed. games.
Under is 8-2 in MIN last 10 on grass.
LAD are 20-6 in their last 26 Wed. games.
LAD are 3-10 in their last 13 overall.
LAD are 3-10 in their last 13 games on grass.
MIN are 5-16 in the last 21 meetings.
Pick: Twins +1.5 -102
Boston (Giolito) at Philadelphia (Luzardo) – 7:05 ET
Under is 6-0-2 in BOS last 8 overall.
Under is 6-0-2 in BOS last 8 on grass.
BOS are 11-3 in their last 14 overall.
PHI are 83-40 in their last 123 home games.
Over is 6-2-1 in Luzardo’s last 9 starts overall.
Over is 5-2-1 in Luzardo’s last 8 starts on grass.
Pick: Red Sox +133
