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**All plays are Listed Pitchers and trends are courtesy of Don Best Sports and are through 4/6/26**
San Diego (King) at Pittsburgh (Keller) – 12:35 ET
Win/Loss
Hot: Pirates are 6-0 in their last 6 vs. National League West.
Pirates are 19-7 in their last 26 Wednesday games.
Pirates are 2-7 in their last 9 home games.
Padres are 2-5 in their last 7 games on grass.
Padres are 2-5 in their last 7 overall.
Over/Under
Hot: Under is 4-0 in Padres last 4 road games.
Hot: Under is 21-4-1 in Pirates last 26 Wednesday games.
Hot: Under is 5-1-1 in Padres last 7 during game 3 of a series.
Under is 6-2-1 in Padres last 9 on grass.
Under is 6-2-1 in Padres last 9 overall.
Under is 3-1-1 in Padres last 5 Wednesday games.
Pick: Padres +100
Philadelphia (Nola) at San Francisco (Mahle) – 3:45 ET
Win/Loss
Hot: Phillies are 4-1 in their last 5 during game 3 of a series.
Hot: Phillies are 4-1 in their last 5 Wednesday games.
Phillies are 24-9 in their last 33 road games vs. a team with a home winning % of less than .400.
Cold: Phillies are 1-6 in their last 7 games vs. a team with a winning % below .400.
Cold: Phillies are 1-5 in their last 6 vs. National League West.
Over/Under
Hot: Under is 4-0-1 in Giants last 5 home games.
Hot: Under is 3-0-1 in Giants last 4 during game 3 of a series.
Hot: Over is 2-0-2 in Phillies last 4 games vs. a team with a winning % below .400.
Hot: Under is 5-1-2 in Giants last 8 on grass.
Hot: Under is 5-1-2 in Giants last 8 overall.
Hot: Over is 4-1-1 in Phillies last 6 Wednesday games.
Pick: Giants +118
St Louis (McGreevy) at Washington (Mikolas) – 4:05 ET
Win/Loss
Nationals are 6-2 in their last 8 vs. National League Central.
Cold: Cardinals are 0-4 in their last 4 road games.
Cold: Nationals are 1-6 in their last 7 home games.
Cold: Cardinals are 3-12 in their last 15 Wednesday games.
Nationals are 8-20 in their last 28 games after losing the first 2 games of a series.
Nationals are 3-7 in their last 10 games vs. a team with a winning % above .600.
Over/Under
Hot: Over is 5-0-1 in Nationals last 6 games vs. a team with a winning % above .600.
Hot: Under is 4-0 in Cardinals last 4 vs. National League East.
Hot: Over is 6-1-1 in Nationals last 8 Wednesday games.
Hot: Under is 6-1 in Nationals last 7 during game 3 of a series.
Under is 21-7-2 in Cardinals last 30 during game 3 of a series.
Over is 5-2 in Nationals last 7 home games.
Pick: Nationals +109
Cincinnati (Singer) at Miami (Perez) – 6:40 ET
Win/Loss
Hot: Marlins are 6-1 in their last 7 home games.
Hot: Marlins are 5-1 in their last 6 during game 3 of a series.
Hot: Reds are 4-1 in their last 5 vs. National League East.
Reds are 9-3 in their last 12 vs. a team with a winning record.
Marlins are 19-7 in their last 26 games on grass.
Reds are 2-6 in their last 8 Wednesday games.
Over/Under
Hot: Over is 6-0 in Marlins last 6 Wednesday games.
Hot: Under is 4-1 in Marlins last 5 during game 3 of a series.
Under is 21-7-3 in Reds last 31 vs. National League East.
Under is 12-4 in Reds last 16 road games vs. a team with a home winning % of greater than .600.
Under is 20-8-3 in Reds last 31 Wednesday games.
Under is 7-3 in Marlins last 10 on grass.
Pick: Reds +118
Arizona (Nelson) at NY Mets (Peterson) – 4:10 ET
Win/Loss
Diamondbacks are 6-2 in their last 8 Wednesday games.
Cold: Diamondbacks are 0-6 in their last 6 road games.
Cold: Diamondbacks are 0-6 in their last 6 road games vs. a team with a home winning % of greater than .600.
Cold: Mets are 0-5 in their last 5 Wednesday games.
Mets are 2-7 in their last 9 during game 2 of a series.
Diamondbacks are 3-8 in their last 11 games on grass.
Over/Under
Hot: Under is 5-0 in Mets last 5 on grass.
Hot: Under is 5-0 in Mets last 5 overall.
Hot: Under is 6-1 in Diamondbacks last 7 Wednesday games.
Hot: Over is 6-1 in Diamondbacks last 7 vs. National League East.
Hot: Under is 4-1 in Mets last 5 home games.
Hot: Under is 4-1 in Mets last 5 during game 2 of a series.
Pick: Diamondbacks +129
Kansas City (Ragans) at Cleveland (Cantillo) – 1:10 ET
Win/Loss
Guardians are 6-2 in their last 8 during game 3 of a series.
Guardians are 19-7 in their last 26 Wednesday games.
Guardians are 24-9 in their last 33 games on grass.
Guardians are 24-9 in their last 33 overall.
Royals are 18-7 in their last 25 during game 3 of a series.
Guardians are 15-6 in their last 21 vs. a team with a winning record.
Over/Under
Hot: Under is 3-0-1 in Guardians last 4 home games vs. a team with a road winning % of less than .400.
Hot: Under is 9-1-3 in Guardians last 13 Wednesday games.
Hot: Under is 5-1 in Royals last 6 road games.
Hot: Under is 4-1-1 in Guardians last 6 vs. a team with a winning record.
Hot: Under is 4-1 in Royals last 5 on grass.
Hot: Under is 4-1 in Royals last 5 overall.
Pick: Royals -109
Baltimore (Bradish) at Chicago White Sox (Burke) – 2:10 ET
Win/Loss
Hot: Orioles are 6-1 in their last 7 vs. American League Central.
Hot: Orioles are 5-1 in their last 6 games vs. a team with a winning % below .400.
Hot: Orioles are 4-1 in their last 5 Wednesday games.
White Sox are 12-40 in their last 52 games after losing the first 2 games of a series.
White Sox are 26-64 in their last 90 during game 3 of a series.
White Sox are 17-41 in their last 58 vs. American League East.
Over/Under
Hot: Over is 4-0 in White Sox last 4 on grass.
Hot: Over is 4-0 in White Sox last 4 overall.
Hot: Under is 4-1 in Orioles last 5 games vs. a team with a winning % below .400.
Under is 12-4 in White Sox last 16 during game 3 of a series.
Under is 6-2 in Orioles last 8 vs. American League Central.
Under is 19-7-2 in Orioles last 28 on grass.
Pick: White Sox +136
Seattle (Woo) at Texas (Gore) – 2:35 ET
Win/Loss
Hot: Rangers are 4-1 in their last 5 games on grass.
Hot: Rangers are 4-1 in their last 5 overall.
Mariners are 10-4 in their last 14 during game 3 of a series.
Cold: Rangers are 1-8 in their last 9 vs. a team with a losing record.
Cold: Rangers are 1-6 in their last 7 during game 3 of a series.
Cold: Rangers are 1-5 in their last 6 home games vs. a team with a losing record.
Over/Under
Hot: Under is 5-0 in Rangers last 5 home games.
Hot: Under is 5-0 in Rangers last 5 home games vs. a team with a losing record.
Hot: Over is 5-0 in Mariners last 5 Wednesday games.
Hot: Over is 5-1-1 in Rangers last 7 on grass.
Hot: Over is 5-1-1 in Rangers last 7 overall.
Hot: Under is 5-1 in Rangers last 6 vs. a team with a losing record.
Pick: Rangers +100
Athletics (Severino) at NY Yankees (Warren) – 7:05 ET
Win/Loss
Hot: Yankees are 5-1 in their last 6 during game 2 of a series.
Yankees are 50-15 in their last 65 home games vs. a team with a road winning % of less than .400.
Yankees are 16-5 in their last 21 home games.
Cold: are 1-7 in their last 8 road games.
Cold: are 1-7 in their last 8 overall.
Cold: are 1-5 in their last 6 vs. a team with a winning record.
Over/Under
Hot: Under is 4-0 in last 4 road games.
Hot: Under is 4-0 in last 4 vs. a team with a winning record.
Hot: Under is 9-1-2 in last 12 Wednesday games.
Hot: Under is 7-1-1 in last 9 vs. American League East.
Hot: Under is 6-1 in Yankees last 7 games vs. a team with a winning % below .400.
Hot: Under is 6-1 in Yankees last 7 home games.
Pick: Yankees -1.5 +115
Detroit (Valdez) at Minnesota (Ober) – 7:40 ET
Win/Loss
Cold: Twins are 0-7 in their last 7 Wednesday games.
Cold: Twins are 0-6 in their last 6 home games vs. a team with a road winning % of less than .400.
Cold: Tigers are 0-4 in their last 4 games on grass.
Cold: Tigers are 0-4 in their last 4 road games.
Cold: Tigers are 0-4 in their last 4 overall.
Cold: Twins are 2-12 in their last 14 games vs. a team with a winning % below .400.
Over/Under
Hot: Under is 12-2 in Twins last 14 on grass.
Hot: Under is 12-2 in Twins last 14 overall.
Hot: Over is 4-1 in Twins last 5 home games vs. a team with a road winning % of less than .400.
Hot: Under is 4-1 in Twins last 5 vs. American League Central.
Under is 7-2 in Tigers last 9 during game 3 of a series.
Under is 12-4-1 in Tigers last 17 road games.
Pick: Twins +136
Milwaukee (Patrick) at Boston (Gray) – 1:35 ET
Win/Loss
Hot: Red Sox are 6-1 in their last 7 games vs. a team with a winning % above .600.
Hot: Red Sox are 5-1 in their last 6 games after losing the first 2 games of a series.
Hot: Brewers are 5-1 in their last 6 games on grass.
Cold: Red Sox are 0-5 in their last 5 games on grass.
Cold: Red Sox are 0-5 in their last 5 overall.
Cold: Brewers are 0-4 in their last 4 interleague road games.
Over/Under
Hot: Under is 5-0-1 in Red Sox last 6 home games.
Hot: Over is 4-0 in Red Sox last 4 interleague games vs. a team with a winning record.
Hot: Under is 5-1 in Brewers last 6 road games.
Hot: Under is 5-1 in Brewers last 6 interleague road games vs. a team with a losing record.
Hot: Over is 4-1 in Red Sox last 5 on grass.
Hot: Over is 4-1 in Red Sox last 5 overall.
Pick: Brewers +119
LA Dodgers (Ohtani) at Toronto (Cease) – 3:07 ET
Win/Loss
Hot: Dodgers are 11-1 in their last 12 road games vs. a team with a home winning % of greater than .600.
Hot: Dodgers are 14-2 in their last 16 road games.
Hot: Dodgers are 7-1 in their last 8 interleague road games.
Cold: Blue Jays are 1-5 in their last 6 interleague home games.
Cold: Blue Jays are 1-4 in their last 5 interleague games.
Cold: Blue Jays are 1-4 in their last 5 vs. National League West.
Over/Under
Hot: Under is 4-0 in Dodgers last 4 overall.
Hot: Under is 6-1 in Dodgers last 7 interleague games.
Hot: Under is 4-1 in Dodgers last 5 vs. a team with a winning record.
Hot: Under is 4-1 in Dodgers last 5 interleague games vs. a team with a winning record.
Under is 15-5 in Dodgers last 20 road games vs. a team with a home winning % of greater than .600.
Under is 14-5-1 in Dodgers last 20 Wednesday games.
Pick: Blue Jays +142
Houston (Javier) at Colorado (Lorenzen) – 3:10 ET
Win/Loss
Hot: Astros are 5-0 in their last 5 games on grass.
Hot: Astros are 5-0 in their last 5 games vs. a team with a winning % below .400.
Hot: Astros are 5-0 in their last 5 overall.
Cold: Rockies are 1-7 in their last 8 interleague home games vs. a team with a winning record.
Cold: Rockies are 9-42 in their last 51 games vs. a team with a winning % above .600.
Cold: Rockies are 2-8 in their last 10 during game 3 of a series.
Over/Under
Hot: Under is 6-0-1 in Astros last 7 vs. National League West.
Hot: Under is 5-0 in Rockies last 5 on grass.
Hot: Over is 5-0 in Astros last 5 on grass.
Hot: Over is 5-0 in Astros last 5 overall.
Hot: Over is 4-0 in Rockies last 4 interleague home games vs. a team with a winning record.
Hot: Under is 7-1 in Rockies last 8 overall.
Pick: Rockies +139
Atlanta (Holmes) at LA Angels (Detmers) – 4:07 ET
Win/Loss
Hot: Braves are 8-0 in their last 8 road games.
Hot: Braves are 6-0 in their last 6 interleague road games.
Hot: Braves are 6-0 in their last 6 road games vs. a team with a losing record.
Cold: Angels are 0-7 in their last 7 during game 3 of a series.
Cold: Angels are 0-6 in their last 6 interleague games vs. a team with a winning record.
Cold: Angels are 0-6 in their last 6 games vs. a team with a winning % above .600.
Over/Under
Hot: Under is 7-0 in Braves last 7 vs. a team with a losing record.
Hot: Under is 7-0 in Braves last 7 interleague games.
Hot: Under is 6-0 in Braves last 6 interleague games vs. a team with a losing record.
Hot: Under is 10-1 in Braves last 11 on grass.
Hot: Under is 10-1 in Braves last 11 overall.
Hot: Over is 5-1 in Braves last 6 road games vs. a team with a losing record.
Pick: Braves -122
Chicago Cubs (Rea) at Tampa Bay (Boyle) – 6:40 ET
Win/Loss
Hot: Cubs are 5-1 in their last 6 Wednesday games.
Hot: Cubs are 4-1 in their last 5 during game 3 of a series.
Hot: Cubs are 4-1 in their last 5 interleague road games.
Cold: Cubs are 0-7 in their last 7 road games.
Cold: Rays are 1-6 in their last 7 games on fieldturf.
Rays are 8-20 in their last 28 overall.
Over/Under
Hot: Over is 5-0 in Rays last 5 during game 3 of a series.
Hot: Over is 9-1-2 in Rays last 12 vs. National League Central.
Hot: Over is 8-1-4 in Rays last 13 Wednesday games.
Hot: Over is 8-1-1 in Rays last 10 interleague games.
Hot: Over is 6-1 in Rays last 7 overall.
Hot: Under is 5-1 in Cubs last 6 interleague road games.
Pick: Cubs -110
