Houston (23-2) at Iowa State (22-3)
When: Monday, February 16th 2026
Where: Hilton Coliseum,
Ames, IA
Time: 6:00 ET | TV: ESPN
Opening Odds: Iowa State -2.5/136.5
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HOUSTON VS IOWA STATE RECENT MEETINGS
Prediction
It’s really hard to go against this Iowa State team at home. They are a perfect 14-0 this season in Ames and 47-2 over the last three seasons. Iowa State is also 11-1 ATS at home against teams with a winning record. The Cyclones bounced back from a tough road loss at TCU and completely dominated Kansas, handing the Jayhawks their worst loss against Iowa State since 1973. Houston has won six straight since a loss at Texas Tech, but have failed to cover their last two games. Iowa State is 4-2 against Houston in the last six meetings and 5-0-1 ATS, including two home wins over the Cougars. This should be an exciting back and forth game and I’ll take the home team here.
Pick: Iowa State -2.5
