Houston vs Duke Odds, Stats and Free Pick [Final Four]

Houston (34-4) vs Duke (35-3)
When: Saturday, April 5th 2025
Where: Alamodome,
San Antonio, TX

Time: 8:49 ET | TV: CBS
Opening Odds: Duke -4.5/136.5

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Houston Cougars L10 Games

Courtesy of Don Best Sports

Duke Blue Devils L10 Games

Courtesy of Don Best Sports


Prediction

This is another great Final Four matchup, but I think Duke is the superior team here. They have the best player in the nation and three of their guards all shot over 40% from three point land. The problem I have with taking Houston is their lack of a high-powered offense. If Duke gets a double-digit lead, that could be it. I’ll lay the points.

Pick: Duke -5

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