Commanders vs Chargers Odds and Free Prediction [10/5/25]

Washington (2-2) at LA Chargers (3-1)
When: Sunday, October 5th 2025
Where: SoFi Stadium,
Inglewood, CA

Time: 4:25 ET | TV: FOX
Opening Odds: Los Angeles -2.5/47.5

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Commanders vs Chargers Recent Meetings

Commanders Injury Report

Player Status/Updated
Deebo SamuelWRQues oct 5 - Heel - 10/3/25
Mike SainristilCBQues Oct 5 - Knee - 10/3/25
Percy ButlerSQues Oct. 05 - Hip - 9/28/25
Jayden DanielsQBQues Oct. 05 - Knee - 9/28/25
John BatesTEQues Oct 05 - Groin - 9/28/25
Noah BrownWRQues Oct. 05 - Knee - 9/28/25
Ale KahoLBQues Oct. 05 - Undisclosed - 9/28/25
Brandon ColemanOTQues Oct. 05 - Lower Body - 9/28/25
Terry McLaurinWROut Oct 5 - Quadricep - 10/3/25
Deatrich WiseDEout for season - Quadricep - 9/12/25
Javontae Jean-BaptisteDEOut indefinitely - Pectoral - 10/1/25
Will HarrisSOut indefinitely - Leg - 9/23/25
Austin EkelerRBOut indefinitely - Shoulder - 9/15/25
Jonathan JonesCBOut indefinitely - Hamstring - 9/17/25
Lucas NiangOTout for season - Knee - 8/12/25
Tyree JacksonTEout for season - Undisclosed - 10/3/25
Sam CosmiOTOut indefinitely - Knee - 8/28/25
Courtesy of Don Best Sports

Chargers Injury Report

Player Status/Updated
Derwin James Jr.SQues Oct 5 - Hip - 10/3/25
Tarheeb StillCBQues Oct 5 - Ankle - 10/3/25
Tucker FiskTEQues Oct 5 - Toe - 10/3/25
Bradley BozemanCQues Oct 5 - Back - 9/28/25
Derius DavisWRQues Oct 5 - Knee - 9/28/25
Trey Pipkins IIIGQues Oct 5 - Knee - 9/28/25
Will DisslyTEQues Oct 5 - Knee - 9/28/25
Trey LanceQBQues Oct 5 - Hand - 9/28/25
Mekhi BectonGQues Oct 5 - Illness - 9/28/25
Otito OgbonniaDLQues Oct 5 - Undisclosed - 9/28/25
Joe AltOTDoubt Oct. 5 - Ankle - 10/1/25
Najee HarrisRBout for season - Achilles - 9/25/25
Khalil MackLBLate Oct - Elbow - 9/17/25
Denzel PerrymanLBOut indefinitely - Ankle - 9/15/25
Josh HarrisLSOut indefinitely - Undisclosed - 8/28/25
Josh FugaDLout for season - Undisclosed - 8/27/25
Jordan OladokunCBout for season - Undisclosed - 8/27/25
Junior ColsonLBout for season - Shoulder - 10/3/25
Deane LeonardDBOut indefinitely - Leg - 8/28/25
Eric RogersCBOut indefinitely - Undisclosed - 8/28/25
Rashawn SlaterOTout for season - Knee - 8/10/25
Savion WashingtonOTOut indefinitely - Undisclosed - 9/6/25
Courtesy of Don Best Sports


Prediction

I love taking good teams when coming off a bad loss. The Chargers fit that category after an embarrassing loss at the New York Giants last week. This is a team that has already beaten division rivals Kansas City and Denver and the Chargers are a top 10 team in both offense and defense. Jayden Daniels is back for Washington, but he’s coming off a knee injury and will be wearing a brace for this game. That may hinder his mobility a bit. L.A. doesn’t have the best home field advantage, but it will be just enough to help them get by the Commanders.

Pick: Chargers -2.5

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