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Saskatchewan Roughriders at Hamilton Tiger-Cats – 7:30 ET (Thursday)
- Under is 4-1 in the last 5 meetings in Hamilton.
- Under is 7-2 in the last 9 meetings.
- Roughriders are 27-10-1 ATS in their last 38 meetings.
Pick: Saskatchewan +11
B.C. Lions at Ottawa Redblacks – 7:30 ET (Friday)
- Under is 3-0-1 in the last 4 meetings in Ottawa.
Pick: British Columbia +7
Winnipeg Blue Bombers at Toronto Argonauts – 4:00 ET (Saturday)
- Blue Bombers are 4-0 ATS in their last 4 meetings.
- Over is 4-0 in the last 4 meetings.
- Over is 5-1 in the last 6 meetings in Toronto.
Pick: Winnipeg -2
Montreal Alouettes at Calgary Stampeders – 9:00 ET (Saturday)
- Alouettes are 6-1 ATS in their last 7 meetings.
- Under is 6-2 in the last 8 meetings.
- Alouettes are 2-6 ATS in their last 8 meetings in Calgary.
Pick: Montreal +20