Wednesday’s MLB Baseball Free Picks & Predictions [7/22/26]

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**All plays are Listed Pitchers and trends are courtesy of Don Best Sports and are through 7/20/26**


NY Mets (Scott) at Milwaukee (Henderson) – 2:10 ET

Win/Loss
Hot: Brewers are 5-0 in their last 5 vs. National League East.
Hot: Brewers are 5-0 in Henderson’s last 5 starts.
Hot: Brewers are 5-0 in Henderson’s last 5 starts on grass.
Mets are 7-22 in their last 29 games vs. a starter with a WHIP less than 1.15.
Mets are 7-19 in their last 26 road games vs. a team with a home winning % of greater than .600.
Mets are 9-23 in their last 32 vs. National League Central.

Over/Under
Hot: Under is 7-0-1 in Scott’s last 8 starts on grass.
Hot: Under is 7-0-1 in Scott’s last 8 starts overall.
Hot: Under is 6-0 in Scott’s last 6 road starts.
Hot: Under is 5-0-1 in Scott’s last 6 starts vs. a team with a winning record.
Hot: Under is 4-0-1 in Scott’s last 5 starts with 5 days of rest.
Hot: Under is 5-1 in Mets last 6 on grass.

Head-to-Head
Over is 5-2 in the last 7 meetings.
Over is 5-2 in the last 7 meetings in Milwaukee.

Pick: Brewers -1.5 +145


Washington (Cavalli) at Colorado (Hughes) – 3:10 ET

Win/Loss
Hot: Nationals are 5-1 in their last 6 road games vs. a team with a losing home record.
Hot: Nationals are 5-1 in their last 6 road games.
Hot: Nationals are 4-1 in Cavalli’s last 5 road starts.
Cold: Nationals are 0-5 in Cavalli’s last 5 starts during game 3 of a series.
Cold: Rockies are 1-10 in their last 11 home games vs. a team with a road winning % of greater than .600.
Cold: Rockies are 1-7 in their last 8 games vs. a starter with a WHIP greater than 1.30.

Over/Under
Hot: Over is 6-0-2 in Cavalli’s last 8 starts following a Quality Start in his last appearance.
Hot: Over is 3-0-1 in Cavalli’s last 4 starts with 4 days of rest.
Hot: Over is 7-1-1 in Cavalli’s last 9 starts vs. a team with a losing record.
Hot: Over is 5-1-1 in Cavalli’s last 7 road starts vs. a team with a losing record.
Hot: Over is 13-3-2 in Cavalli’s last 18 starts on grass.
Hot: Over is 4-1-1 in Rockies last 6 home games vs. a right-handed starter.

Head-to-Head
Hot: Under is 4-1 in the last 5 meetings in Colorado.
Hot: Nationals are 4-1 in the last 5 meetings in Colorado.
Under is 5-2 in the last 7 meetings.

Pick: Rockies +121


LA Dodgers (Lauer) at Philadelphia (Nola) – 6:40 ET

Win/Loss
Hot: Dodgers are 6-0 in Lauer’s last 6 starts.
Hot: Dodgers are 6-0 in Lauer’s last 6 starts on grass.
Hot: Phillies are 5-0 in Nola’s last 5 starts vs. a team with a winning record.
Cold: Phillies are 0-4 in Nola’s last 4 starts.
Cold: Phillies are 0-4 in Nola’s last 4 starts on grass.
Phillies are 2-6 in Nola’s last 8 Wednesday starts.

Over/Under
Hot: Under is 7-0 in Dodgers last 7 during game 3 of a series.
Hot: Under is 5-1 in Phillies last 6 on grass.
Hot: Under is 5-1 in Phillies last 6 overall.
Hot: Under is 4-1-1 in Nola’s last 6 starts with 5 days of rest.
Hot: Under is 4-1 in Phillies last 5 home games vs. a team with a road winning % of greater than .600.
Hot: Over is 4-1 in Phillies last 5 Wednesday games.

Head-to-Head
Dodgers are 3-7 in the last 10 meetings in Philadelphia.

Pick: CLICK HERE

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San Diego (King) at Atlanta (Perez) – 7:15 ET

Win/Loss
Hot: Padres are 5-0 in King’s last 5 Wednesday starts.
Hot: Braves are 5-1 in their last 6 games vs. a right-handed starter.
Hot: Padres are 8-2 in King’s last 10 starts with 4 days of rest.
Cold: Padres are 0-4 in King’s last 4 road starts.
Cold: Padres are 1-9 in their last 10 vs. a team with a winning record.
Cold: Padres are 1-5 in their last 6 road games vs. a team with a home winning % of greater than .600.

Over/Under
Hot: Over is 5-0-1 in King’s last 6 Wednesday starts.
Hot: Under is 5-0 in Braves last 5 vs. National League West.
Hot: Under is 5-0 in King’s last 5 starts vs. a team with a winning record.
Hot: Over is 4-0 in Braves last 4 home games vs. a right-handed starter.
Hot: Under is 4-0 in Padres last 4 vs. a team with a winning record.
Hot: Under is 4-0 in Padres last 4 road games vs. a team with a winning record.

Head-to-Head
Hot: Under is 4-0-1 in the last 5 meetings in Atlanta.
Hot: Under is 7-1-2 in the last 10 meetings.
Padres are 19-7 in the last 26 meetings.
Padres are 8-3 in the last 11 meetings in Atlanta.

Pick: Braves -113


Minnesota (Ober) at Cleveland (Cecconi) – 6:40 ET

Win/Loss
Hot: Twins are 6-0 in Ober’s last 6 starts with 4 days of rest.
Hot: Guardians are 4-1 in Cecconi’s last 5 home starts.
Guardians are 6-2 in their last 8 games on grass.
Cold: Guardians are 0-5 in Cecconi’s last 5 starts during game 3 of a series.
Cold: Guardians are 1-8 in Cecconi’s last 9 starts following a team loss in their previous game.
Cold: Twins are 2-8 in Ober’s last 10 starts vs. American League Central.

Over/Under
Hot: Over is 4-0 in Cecconi’s last 4 starts vs. American League Central.
Hot: Under is 4-0 in Cecconi’s last 4 starts during game 3 of a series.
Hot: Under is 4-0 in Twins last 4 games vs. a starter with a WHIP greater than 1.30.
Hot: Under is 4-0 in Ober’s last 4 road starts vs. a team with a winning record.
Hot: Over is 3-0-1 in Ober’s last 4 starts with 4 days of rest.
Hot: Under is 6-1 in Ober’s last 7 starts vs. a team with a winning record.

Head-to-Head
Hot: Over is 5-1 in the last 6 meetings in Cleveland.
Twins are 5-14 in the last 19 meetings in Cleveland.

Pick: Guardians -120


Tampa Bay (Jax) at Toronto (Fisher) – 7:07 ET

Win/Loss
Hot: Rays are 4-0 in Jax’s last 4 starts with 4 days of rest.
Hot: Rays are 4-1 in their last 5 Wednesday games.
Blue Jays are 9-3 in their last 12 games after losing the first 2 games of a series.
Cold: Rays are 1-6 in their last 7 road games vs. a team with a losing home record.
Cold: Rays are 1-6 in their last 7 road games.
Cold: Blue Jays are 1-5 in their last 6 vs. a team with a winning record.

Over/Under
Hot: Over is 3-0-1 in Jax’s last 4 starts vs. a team with a losing record.
Over is 6-2 in Blue Jays last 8 games vs. a right-handed starter.
Over is 3-1-1 in Rays last 5 vs. a team with a losing record.
Over is 3-1-1 in Jax’s last 5 starts overall.
Under is 12-5 in Rays last 17 road games vs. a team with a losing record.
Over is 7-3 in Blue Jays last 10 overall.

Head-to-Head
Hot: Rays are 6-1 in the last 7 meetings.
Under is 6-2-1 in the last 9 meetings.

Pick: Rays -105

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Baltimore (Bradish) at Boston (ACTION) – 7:10 ET

Win/Loss
Hot: Red Sox are 9-0 in their last 9 vs. American League East.
Hot: Red Sox are 7-0 in their last 7 games vs. a right-handed starter.
Hot: Red Sox are 7-0 in their last 7 vs. a team with a losing record.
Cold: Orioles are 4-22 in their last 26 road games vs. a team with a winning record.
Cold: Orioles are 2-8 in their last 10 games vs. a starter with a WHIP less than 1.15.
Cold: Red Sox are 1-4 in their last 5 Wednesday games.

Over/Under
Hot: Over is 4-0 in Orioles last 4 vs. American League East.
Hot: Over is 9-1-2 in Orioles last 12 Wednesday games.
Hot: Under is 8-1 in Orioles last 9 games vs. a left-handed starter.

Head-to-Head
Orioles are 6-2 in the last 8 meetings in Boston.
Over is 5-2 in the last 7 meetings.
Orioles are 3-8 in the last 11 meetings.

Pick: Orioles +130


Chicago White Sox (Kay) at Texas (Alexander) – 8:05 ET

Win/Loss
Hot: White Sox are 4-0 in their last 4 games on grass.
Hot: White Sox are 4-0 in their last 4 vs. American League West.
Hot: Rangers are 11-1 in their last 12 home games vs. a left-handed starter.
Cold: Rangers are 1-5 in their last 6 Wednesday games.
Cold: Rangers are 1-4 in their last 5 vs. a team with a winning record.
Cold: Rangers are 1-4 in their last 5 vs. American League Central.

Over/Under
Hot: Over is 6-0 in Rangers last 6 during game 3 of a series.
Hot: Over is 6-0 in Rangers last 6 games vs. a left-handed starter.
Hot: Over is 5-0 in Rangers last 5 vs. a team with a winning record.
Hot: Over is 4-0 in Rangers last 4 games vs. a starter with a WHIP greater than 1.30.
Hot: Over is 11-1 in Rangers last 12 home games vs. a team with a losing road record.
Hot: Under is 5-1 in White Sox last 6 Wednesday games.

Head-to-Head
Cold: White Sox are 1-10 in the last 11 meetings in Texas.
White Sox are 6-20 in the last 26 meetings.

Pick: White Sox -101


Pittsburgh (Keller) at NY Yankees (Cole) – 1:05 ET

Win/Loss
Hot: Pirates are 5-1 in their last 6 road games vs. a right-handed starter.
Hot: Pirates are 5-1 in their last 6 interleague games vs. a right-handed starter.

Over/Under
Hot: Under is 9-0 in Yankees last 9 during game 3 of a series.
Hot: Over is 6-0 in Pirates last 6 during game 3 of a series.
Hot: Under is 4-0 in Yankees last 4 games vs. a starter with a WHIP greater than 1.30.

Head-to-Head
Hot: Over is 6-0 in the last 6 meetings.
Hot: Over is 5-1 in the last 6 meetings in New York.
Cold: Pirates are 3-12 in the last 15 meetings in New York.
Cold: Pirates are 1-4 in the last 5 meetings.

Pick: Yankees -1.5 +120

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San Francisco (Roupp) at Kansas City (Lugo) – 2:10 ET

Win/Loss
Hot: Royals are 5-0 in Lugo’s last 5 interleague starts.
Hot: Giants are 6-1 in Roupp’s last 7 road starts vs. a team with a losing record.
Hot: Royals are 5-1 in their last 6 home games.
Cold: Royals are 0-5 in Lugo’s last 5 Wednesday starts.
Cold: Giants are 0-4 in Roupp’s last 4 starts with 4 days of rest.
Cold: Giants are 1-7 in Roupp’s last 8 road starts.

Over/Under
Hot: Under is 5-0-1 in Roupp’s last 6 road starts vs. a team with a losing record.
Hot: Over is 5-0 in Lugo’s last 5 starts with 4 days of rest.
Hot: Over is 4-0 in Royals last 4 during game 3 of a series.
Hot: Over is 4-0 in Lugo’s last 4 interleague starts.
Hot: Over is 3-0-1 in Lugo’s last 4 starts vs. a team with a losing record.
Hot: Over is 3-0-1 in Roupp’s last 4 starts on grass.

Head-to-Head
Hot: Under is 6-1 in the last 7 meetings in Kansas City.
Hot: Under is 4-1 in the last 5 meetings.
Giants are 5-2 in the last 7 meetings in Kansas City.

Pick: Royals +106


Athletics (Jump) at Arizona (Kelly) – 3:40 ET

Win/Loss
Hot: A’s are 4-1 in their last 5 interleague road games vs. a team with a winning record.
Hot: A’s are 4-1 in their last 5 interleague road games vs. a right-handed starter.
Diamondbacks are 6-2 in their last 8 interleague home games vs. a left-handed starter.
Cold: Diamondbacks are 0-6 in their last 6 interleague games.
Cold: A’s are 0-5 in Jump’s last 5 starts.
Cold: A’s are 0-5 in Jump’s last 5 starts on grass.

Over/Under
Hot: Under is 6-0-1 in Kelly’s last 7 starts overall.
Hot: Under is 6-0 in Kelly’s last 6 starts following a team loss in their previous game.
Hot: Under is 5-0-1 in Diamondbacks last 6 vs. American League West.
Hot: Under is 5-0-1 in Kelly’s last 6 starts on grass.
Hot: Under is 5-0 in Diamondbacks last 5 interleague games.
Hot: Under is 4-0 in Jump’s last 4 road starts.

Head-to-Head
Hot: Under is 5-0-1 in the last 6 meetings.

Pick: Diamondbacks -112


Cincinnati (Singer) at Seattle (Hancock) – 3:40 ET

Win/Loss
Hot: Mariners are 5-1 in their last 6 home games.
Hot: Mariners are 5-1 in their last 6 vs. a team with a losing record.
Hot: Reds are 5-1 in Singer’s last 6 starts following a Quality Start in his last appearance.
Cold: Reds are 0-7 in Singer’s last 7 starts vs. a team with a winning record.
Cold: Mariners are 0-5 in their last 5 Wednesday games.
Cold: Reds are 0-5 in Singer’s last 5 starts during game 3 of a series.

Over/Under
Hot: Over is 5-0-3 in Mariners last 8 overall.
Hot: Over is 5-0-1 in Singer’s last 6 road starts vs. a team with a winning record.
Hot: Over is 4-0-2 in Mariners last 6 interleague home games.
Hot: Over is 4-0-2 in Mariners last 6 interleague home games vs. a team with a losing record.
Hot: Over is 5-0 in Hancock’s last 5 starts with 9 or more days of rest.
Hot: Over is 3-0-2 in Mariners last 5 interleague games.

Head-to-Head
Under is 7-3-1 in the last 11 meetings in Seattle.
Cold: Reds are 1-11 in the last 12 meetings in Seattle.
Reds are 6-22 in the last 28 meetings.

Pick: Reds +136

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St Louis (Dobbins) at LA Angels (Detmers) – 4:07 ET

Win/Loss
Hot: Angels are 4-0 in Detmers’ last 4 starts following a Quality Start in his last appearance.
Hot: Angels are 4-1 in their last 5 Wednesday games.
Cardinals are 20-7 in their last 27 road games vs. a left-handed starter.
Cold: Angels are 0-5 in Detmers’ last 5 home starts vs. a team with a winning record.
Cold: Cardinals are 0-4 in their last 4 during game 3 of a series.
Cold: Angels are 1-8 in their last 9 games vs. a starter with a WHIP less than 1.15.

Over/Under
Hot: Under is 7-0 in Angels last 7 overall.
Hot: Under is 7-0 in Angels last 7 on grass.
Hot: Under is 6-0 in Angels last 6 games vs. a right-handed starter.
Hot: Under is 6-0 in Detmers’ last 6 home starts.
Hot: Under is 5-0 in Detmers’ last 5 starts following a team loss in their previous game.
Hot: Under is 5-0 in McGreevy’s last 5 starts during game 3 of a series.

Head-to-Head
Hot: Over is 4-1 in the last 5 meetings in Los Angeles.
Over is 19-7 in the last 26 meetings.
Cardinals are 5-2 in the last 7 meetings in Los Angeles.
Cold: Cardinals are 1-4 in the last 5 meetings.

Pick: Angels -115


Detroit (Montero) at Chicago Cubs (Rea) – 8:05 ET

Win/Loss
Hot: Cubs are 7-1 in their last 8 during game 3 of a series.
Hot: Cubs are 7-1 in their last 8 games vs. a starter with a WHIP less than 1.15.
Hot: Tigers are 6-1 in their last 7 games vs. a starter with a WHIP greater than 1.30.
Cold: Cubs are 0-5 in Rea’s last 5 starts following a team loss in their previous game.
Cold: Cubs are 0-4 in Rea’s last 4 home starts vs. a team with a losing record.
Cold: Cubs are 1-5 in Rea’s last 6 interleague starts.

Over/Under
Hot: Over is 6-0-2 in Rea’s last 8 Wednesday starts.
Hot: Over is 5-0 in Tigers last 5 vs. National League Central.
Hot: Over is 4-0-1 in Montero’s last 5 starts during game 3 of a series.
Hot: Over is 3-0-2 in Rea’s last 5 starts during game 3 of a series.
Hot: Under is 4-0 in Tigers last 4 Wednesday games.
Hot: Over is 3-0-1 in Rea’s last 4 starts with 4 days of rest.

Head-to-Head
Over is 7-3 in the last 10 meetings in Chicago.

Pick: Cubs -110


Miami (Alcantara) at Houston (Lambert) – 8:10 ET

Win/Loss
Hot: Astros are 6-0 in Lambert’s last 6 starts vs. a team with a winning record.
Hot: Marlins are 5-0 in Alcantara’s last 5 Wednesday starts.
Hot: Marlins are 4-0 in Alcantara’s last 4 starts during game 3 of a series.
Cold: Marlins are 0-7 in their last 7 overall.
Cold: Marlins are 0-7 in their last 7 games on grass.
Cold: Marlins are 0-4 in their last 4 interleague games.

Over/Under
Hot: Under is 5-0-1 in Lambert’s last 6 home starts.
Hot: Under is 4-0 in Lambert’s last 4 starts during game 3 of a series.
Hot: Under is 6-1-1 in Lambert’s last 8 starts on grass.
Hot: Under is 5-1 in Astros last 6 home games vs. a team with a losing road record.
Hot: Under is 5-1 in Marlins last 6 Wednesday games.
Hot: Over is 5-1 in Alcantara’s last 6 starts following a team loss in their previous game.

Head-to-Head
Hot: Over is 6-0 in the last 6 meetings.
Hot: Over is 4-1 in the last 5 meetings in Houston.
Cold: Marlins are 0-5 in the last 5 meetings in Houston.
Cold: Marlins are 1-8 in the last 9 meetings.

Pick: Marlins +105


Pittsburgh (Chandler) at NY Yankees (Fried) – 7:05 ET

Win/Loss
Hot: Pirates are 5-1 in their last 6 road games vs. a right-handed starter.
Hot: Pirates are 5-1 in their last 6 interleague games vs. a right-handed starter.

Over/Under
Hot: Under is 9-0 in Yankees last 9 during game 3 of a series.
Hot: Over is 6-0 in Pirates last 6 during game 3 of a series.
Hot: Under is 4-0 in Yankees last 4 games vs. a starter with a WHIP greater than 1.30.

Head-to-Head
Hot: Over is 6-0 in the last 6 meetings.
Hot: Over is 5-1 in the last 6 meetings in New York.
Cold: Pirates are 3-12 in the last 15 meetings in New York.
Cold: Pirates are 1-4 in the last 5 meetings.

Pick: Pirates +146


Baltimore (Kremer) at Boston (Bennett) – 1:35 ET

Win/Loss
Hot: Red Sox are 9-0 in their last 9 vs. American League East.
Hot: Red Sox are 7-0 in their last 7 games vs. a right-handed starter.
Hot: Red Sox are 7-0 in their last 7 vs. a team with a losing record.
Cold: Orioles are 4-22 in their last 26 road games vs. a team with a winning record.
Cold: Orioles are 2-8 in their last 10 games vs. a starter with a WHIP less than 1.15.
Cold: Red Sox are 1-4 in their last 5 Wednesday games.

Over/Under
Hot: Over is 4-0 in Orioles last 4 vs. American League East.
Hot: Over is 9-1-2 in Orioles last 12 Wednesday games.
Hot: Under is 8-1 in Orioles last 9 games vs. a left-handed starter.

Head-to-Head
Orioles are 6-2 in the last 8 meetings in Boston.
Over is 5-2 in the last 7 meetings.
Orioles are 3-8 in the last 11 meetings.

Pick: Red Sox -1.5 +145