Cleveland (81-75) at Boston (84-72)
When: Tuesday, September 22nd 2026
Where: Fenway Park,
Boston, MA
Time: 6:45 ET | TV: mlb.tv
Opening Odds: Boston -118/7
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Guardians vs Red Sox Recent Meetings
Prediction
Two playoff teams will engage in a three-game set at Fenway Park this week. The series means more to the Guardians, as they haven’t officially clinched a postseason berth and could go in as a wild card or division winner. The Red Sox are all but locked into a series with the Yankees next week. Both pitchers have been solid, but I trust Messick more. Cleveland is a live dog here.
Pick: Guardians +115
