Chargers vs 49ers Preview & Free Pick [November 13th 2022]

LA Chargers (5-3) at San Francisco (4-4)
When: Sunday, November 13th 2022
Where: Levi’s Stadium,
Santa Clara, CA
Time: 8:20 ET | TV: NBC
Opening Odds: San Francisco -3.5/47.5

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Two second-place teams will do battle at Levi’s Stadium on Sunday Night Football, as the San Francisco 49ers host the Los Angeles Chargers. Both teams have been a little inconsistent this season, but are still in the thick of the playoff race in their respective conferences. L.A.’s Justin Herbert is having a solid season despite battling through a rib injury and not having his top two receivers for the majority of the season. The Chargers have been much better on the road and improved to 3-1 away from SoFi Stadium with a hard-fought 20-17 win at the Atlanta Falcons last Sunday. Rookie Cameron Dicker, the third kicker Los Angeles has used this season, split the uprights on the final play of the game. The Chargers have now won four of five to improve to 5-3 on the season, but are still -22 in point differential.

The Niners are getting healthy again on defense and it’s showing. San Fran snapped a two-game skid with a dominating 31-14 victory at the Los Angeles Rams on Oct. 30 and are coming off their bye. The 49ers expect to have Deebo Samuel back this week after he was a full participant in practice Wednesday. Samuel missed the Week 8 victory over the Rams with a hamstring injury and will be playing with new running back Christian McCaffrey for the first time. Linebacker Dre Greenlaw (calf) returned to practice Wednesday after also sitting out in Week 8. Defensive tackle Arik Armstead has a hairline fracture in his right leg and will be out a while. The Chargers have won the past five in the series, but they haven’t played since L.A. won 29-27 in 2018. The teams have split the past 10 meetings against the spread.


Los Angeles came out of its bye on Sunday and won in Atlanta even though Herbert was missing his top two receivers in Mike Williams and Keenan Allen. Neither will play again this Sunday against a really good San Francisco defense. Allen (hamstring) and Williams (ankle), who combined for 2,284 yards and 182 receptions in 2021, have only shared the field for a few offensive series this season. Herbert is averaging 281.8 yards per game with 13 touchdowns to five interceptions. He is on pace for just under 4,900 yards passing after throwing for 5,014 yards and 38 TDs last season. The Chargers are one of the worst rushing teams in the league, averaging 89.1 yards per game. Los Angeles is one of five teams rushing for less than 90 yards per game. Defensive lineman Austin Johnson was lost for the season after he fractured his knee and sprained his MCL against the Falcons.


The Niners completed the season sweep of the defending Super Bowl champion Rams with a 31-14 win in L.A. last week. McCaffrey became the 11th player in NFL history with a rushing touchdown, a passing touchdown and a receiving touchdown in one game. He rushed for 94 yards and a touchdown on 18 carries and caught eight passes for 55 yards and a touchdown. The 49ers are averaging 22.0 points per game and are seventh in the NFL with a 44.3 percent third-down conversion rate. Since taking over the quarterback position from an injured Trey Lance, Jimmy Garoppolo is averaging 241.6 passing yards per game and 11 TDs with four interceptions. The 49ers are 6-1 ATS in their last seven games against teams with a winning record.

Without their top wide receivers and a zero running game, the Chargers will find it difficult to score points against the Niners. San Fran now has a double-threat in Samuel and McCaffrey to help Garoppolo. This game could get ugly.

Week 10 NFL Staff Selections

Pick: 49ers -7